Patient-important outcomes and core outcome sets: increased attention needed!
نویسندگان
چکیده
منابع مشابه
Core harm outcome sets developed by drug are needed to allow informed risk-benefit decision making
Good information on drug harm is vital to inform riskbenefit decisions and undertake robust cost effectiveness analysis. Harm information in peer-reviewed articles have been found not to be useful for this purpose. Regulators require pharmaceutical companies to produce product information documents (Europe:SmPC, US: USPI). These documents contain comprehensive information on the known harm of a...
متن کاملDeveloping core outcomes sets: methods for identifying and including patient-reported outcomes (PROs)
BACKGROUND Synthesis of patient-reported outcome (PRO) data is hindered by the range of available PRO measures (PROMs) composed of multiple scales and single items with differing terminology and content. The use of core outcome sets, an agreed minimum set of outcomes to be measured and reported in all trials of a specific condition, may improve this issue but methods to select core PRO domains ...
متن کاملCore outcome sets and systematic reviews
Systematic reviews seek to bring together research evidence to answer the question for the review. The reviewers usually wish to compare, contrast and, if appropriate, combine the findings of the existing research studies. However, these intentions are often thwarted by inconsistencies in the outcomes that were measured and reported in the individual studies. This, in turn, makes it difficult f...
متن کاملCore outcome sets and trial registries
Some reasons for registering trials might be considered as self-serving, such as satisfying the requirements of a journal in which the researchers wish to publish their eventual findings or publicising the trial to boost recruitment. Registry entries also help others, including systematic reviewers, to know about ongoing or unpublished studies and contribute to reducing research waste by making...
متن کاملPatient-important outcomes in registered diabetes trials.
CONTEXT Concerns about the safety and efficacy of diabetes interventions persist, in part because randomized clinical trials (RCTs) have not measured their effect on patient-important outcomes, ie, death and quality of life (morbidity, pain, function). OBJECTIVE To systematically determine the extent to which ongoing and future RCTs in diabetes will ascertain patient-important outcomes. DAT...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 2019
ISSN: 0007-0912
DOI: 10.1016/j.bja.2019.02.007